Here are some "general" tips for safe, single-pilot IFR, gleaned from
Larry Bartlett's refresher course. These tips do not represent the "meat
and potatoes" of the video course, but are thrown in at a couple of
points as generalities. How many agree with these :

1) No Single-Pilot, single engine IFR in IMC at night
2) No S-P Multi-engine IFR with MEA's higher than the aircraft's SE
performance
3) No S-P IFR in IMC without dual vacuum sources, and strong
preference for dual alrternators.
4) Keep VFR weather within range of the aircraft at all times, and
know where it is
5) Avoid S-P circling approaches in IMC, and definitely not at
night or close to minimums