AES wrote:
Seems to me, as a broad general proposition:

1) Consistent use of North up is better for longer-term navigation or
course planning, when you're zoomed out on the map and asking, "Where am
I in the big picture?" or "What course should I take to reach a given
(distant) destination?" (or to avoid things I should avoid).

Better chance of identifying major landmarks (lakes, mountain peaks)
correctly and understanding the broad situation.

2) Track up better for short-term maneuvering, when you're asking "What
should I be looking for, and what maneuver do I have to make, in the
next few minutes?"

Excellent analysis. This is why I use both sectional/Low Alt chart and GPS.
I always fold the map(s) to a reasonable sized rectangle to get the big
picture enroute, alwyas North Up. The GPS is Track Up but a much smaller
area than the sectiona and/or Low Alt. chart. I can always tilt the chart
as needed if I want a track relative view, no biggie.

Situational awareness is the key... whatever works go for it. But I never
fly without charts, even though I do love the GPS, I still follow my progress
on the chart.