Tony wrote:

If
the engines were not turbocharged I'd be betting improper leaning for
the density altitude would have a factor, but have no experience at all
with turbocharged engines.

FWIW, the mixture of my turbo-normalized Bonanza is not leaned for a
high-density airport take off. Doing so results in higher than desired CHT
and turbo-inlet temperatures (TIT), which is not a healthy scenario for the
engine that is delivering full horsepower.

By no means am I a turbo expert, but had the Aerostar in this accident been
equipped with turbocharged engines, I would be surprised to learn that it
would need to be leaned for a density altitude take-off of only 4,000 feet.

--
Peter