The sim is better than real life. I've done both. In the little planes,
when u need to urinate, you do it in your pants or into a container. As
for the other bodily functions, you just gotta hold it and hope that there
isn't alot of traffic ahead of you before its your turn to land. (And the
pilots wonder why more women don't want to deal with this).

In the little planes, you are oftentimes dealing with 1960s technology.
The little planes are either too hot or too cold. They can't get you
where you want to go unless you have an IFR license and a capable plane.
In the little planes, you have to worry about other marginally trained
pilots running into you (either on the ground, mid-air, or in the traffic
pattern).

In the little planes, you will waste at least $100K between the training,
equipment, insurance, gas, etc. (Better off buying a really nice BMW or
Audi or Porsche, which will get you where you want in less time, and where
you can pull over at a rest stop when you want).

And, best of all, in the sim world you can fly into and out of Megis Field
to your heart's content!