Looking for facts about high compression pistons

Since I have to overhaul my O-360 engine I am trying to assess the
facts and old wive tales about using higher than 8.5:1 pistons. I am
not concerned about running autogas.

I fly at high altitudes. Usually 10500'-12,500' and up to 17,500'
when over the Rockies. My home airport is around 6,800' MSL with
density altitudes at take-off up to 10,000' in the summer.

My concern is whether up to 10:1 pistons reduces my expected TBO (2000
hours) or causes other problems.

Ron Lee