Mythbusters and explosive decompression

Also, if the test was done on the ground then of course nothing would
happen. It needs to done in a wind tunnel that is depressurized to
simulate
30K feet.

Or, you can just do what they did, and pressurize it on the ground to get
the same pressure differential.

A small bullet hole will not cause much of a structural problem--you aren't
going to see an entire fuselage section ripping off because of aerodynamic
forces. What they did with the shaped charge might cause some problems, but
otherwise the slipstream wouldn't be much of an issue (structure-wise).