Parcel Delivery by UAV (Unmanned Aerial Vehicle)

Accidents and lawsuits would definitely give these big businesses a
problem. But big business usually finds ways to cope and get its
way if there is enough profit. E g air liner crashes and the cost of
safety measures versus the often cheaper move of paying the
litigation or its insurance costs.
IMHO what might well kill it off is the profit motive itself in other
parts of the economy. I think there would be enough people who
would hijack and steal these drones and it would be very difficult to
prevent or catch them. The scenario now gets horrific. The drones
would become heavily armed and fight off intruders. So we dont
need Skynet to nuke us into near oblivion - the oblivious
consumers would hardly notice terminators evolving and new
forms of gang war and anti drone vigilantes becoming the norm
and topics of documentaries and movies.
Bring back Marvin the Paranoid Android.