Boston to Roanoke to Nashville

I am thinking of taking a week or so and fly south. Would appreciate any
recommendations of places to go, esp. interesting scenary or historical
interest (that is near an airport.....).

Right now my vague plans include..


... a ride down the Hudson Valley Corridor past Manhattan.
... fly down the NJ coast, perhaps stop at Cape May
... stay along the coast, east of Washington DC
... stop at Tangier Island in the Chesapeake Bay?
... west past Charlottesville, stop at Luray Caverns.... (yes I know it is
tacky, been there twice by car)
... aerial tour of Shenandoah Valley