long range aircraft flying short-range routes?

Hi, this is my very first post.
As you see, Im a bit of Tupolev fan hehe, and would like if someone could give me some clearity on this.


TU 204-300 has a capacity of 142 pax. and can fly non stop between Moscow - Vladivostok, which is about 6.500km

Could this airplane be easily used for short routes, like the A320 which has also about 150 pax. (business + economy).


Or is it really requierd to have an airplane specially designed for short routes fly only on those?
Thanks in advance for your replies!