Anyway, why I asked this Q was because I was wondering what the
different weight distribution patterns would do to the aircraft's
piloting.

Passengers are strapped to seats for takeoff and landing. On the average this distributes the weight well enough (although I'm sure that if a plane got loaded with all sumo wrestlers in the back and all children in the front, the flight attendant
would notify the pilot who would then make a decision as to whether or not the W&B needed to be calculated more precisely)

Cargo does not have this automatic distribution mechanism, and I'd assume that the containers are distributed appropriately in the hold, though I don't know if it would be by weighing or estimation.

Yes, weight and balance issues are important to big planes too.

Jose
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