Thanks Marco,
I went down that path, tripping a bit with conflicts with other software - upside is I refreshed my /usr/local. I got the command line "wine" working, but even the GUI install of LXSim I had working before failed. I got a windows popup window that said "CoCreateInstance failed; code 0x8004154". Ok then ... stumbled past about 3 of these to a possibly complete installation. But launching fails with

0009:err:dbghelp_stabs:stabs_parse Unknown stab type 0x0a
0009:err:dbghelp_stabs:stabs_parse Unknown stab type 0x0a
wine: Unhandled page fault on write access to 0x00000038 at address 0x61b675 (thread 0009), starting debugger...

Looks like it's VMware or Parallels for me.

On Sunday, January 28, 2018 at 2:47:29 PM UTC-6, Marco wrote:
....

I used: https://www.davidbaumgold.com/tutorials/wine-mac/
Slightly more work but it is also easy to follow.
Parallels is wine, in a commercial way.
I do not run an LX program but use this for SeeYou. Runs OK.