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Heart trouble



 
 
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  #1  
Old July 15th 07, 01:53 AM posted to rec.aviation.piloting
Mortimer Schnerd, RN[_2_]
external usenet poster
 
Posts: 597
Default Heart trouble

Viperdoc wrote:
Coumadin is the chemical name, while Warfarin was the trade name. It derived
from Wisconsin Alumni Research Foundation, where the drug was first
investigated.



Have I lost my mind? Here's something from the prescribing information page of:

http://www.bms.com/cgi-bin/anybin.pl...SEQ=91&key=PPI


DESCRIPTION

COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by
inhibiting vitamin K-dependent

coagulation factors. Chemically, it is 3-(-acetonylbenzyl)-4-hydroxycoumarin and
is a racemic mixture of the

R- and S-enantiomers. Crystalline warfarin sodium is an isopropanol clathrate.
The crystallization of warfarin

sodium virtually eliminates trace impurities present in amorphous warfarin. Its
empirical formula is C19 H15 NaO4,

and its structural formula may be represented by the following:



Looking at this, it sure looks like warfarin is the generic name and Coumadin is
the brand name. At least to me....




--
Mortimer Schnerd, RN
mschnerdatcarolina.rr.com






  #2  
Old July 15th 07, 10:34 PM posted to rec.aviation.piloting
Big John
external usenet poster
 
Posts: 310
Default Heart trouble

MS

My HMO only pays for generic (if there is one) and they give me
Coumadin??????????????

Big John
************************************************** *


On Sat, 14 Jul 2007 20:53:28 -0400, "Mortimer Schnerd, RN"
mschnerdatcarolina.rr.com wrote:

Viperdoc wrote:
Coumadin is the chemical name, while Warfarin was the trade name. It derived
from Wisconsin Alumni Research Foundation, where the drug was first
investigated.



Have I lost my mind? Here's something from the prescribing information page of:

http://www.bms.com/cgi-bin/anybin.pl...SEQ=91&key=PPI


DESCRIPTION

COUMADIN (crystalline warfarin sodium) is an anticoagulant which acts by
inhibiting vitamin K-dependent

coagulation factors. Chemically, it is 3-(-acetonylbenzyl)-4-hydroxycoumarin and
is a racemic mixture of the

R- and S-enantiomers. Crystalline warfarin sodium is an isopropanol clathrate.
The crystallization of warfarin

sodium virtually eliminates trace impurities present in amorphous warfarin. Its
empirical formula is C19 H15 NaO4,

and its structural formula may be represented by the following:



Looking at this, it sure looks like warfarin is the generic name and Coumadin is
the brand name. At least to me....


  #3  
Old July 16th 07, 01:34 AM posted to rec.aviation.piloting
Tina
external usenet poster
 
Posts: 500
Default Heart trouble

Warfarin is the generic form. If you're getting Coumadin it may be
your MD's Rx said 'no substitutions'. I know of several anti-coag
clinics that do that, their staff claims there is greater batch to
batch variation in the warfarin than in the Coumadin. I have never
seen the charts they claim demonstrates this, so that's hear-say only.


  #4  
Old July 16th 07, 03:12 AM posted to rec.aviation.piloting
RomeoMike
external usenet poster
 
Posts: 136
Default Heart trouble



Big John wrote:
MS

My HMO only pays for generic (if there is one) and they give me
Coumadin??????????????

Big John


Coumadin is the brand name for warfarin sodium. Same thing. For any
doubters a source is the Physicians Desk Reference, 61st Ed., page 898.
  #5  
Old July 16th 07, 03:26 AM posted to rec.aviation.piloting
Tina
external usenet poster
 
Posts: 500
Default Heart trouble

If ordered as Coumadin you'll pay one price, if ordered in the generic
(unbranded) form, you'll pay a lower price. Some of the staff at the
anti coag clinic at Duke's Private Diagnostic Clinic ask their
patients to order Coumadin since they find it's easier to control
their INR. Others may have found otherwise, but the price difference
is real.


  #6  
Old July 16th 07, 04:19 AM posted to rec.aviation.piloting
Mortimer Schnerd, RN[_2_]
external usenet poster
 
Posts: 597
Default Heart trouble

RomeoMike wrote:
Big John wrote:
MS

My HMO only pays for generic (if there is one) and they give me
Coumadin??????????????

Big John


Coumadin is the brand name for warfarin sodium. Same thing. For any
doubters a source is the Physicians Desk Reference, 61st Ed., page 898.



Thank you. I was beginning to think I'd lost it. Though, as I think about it,
the day is still young....



--
Mortimer Schnerd, RN
mschnerdatcarolina.rr.com


  #7  
Old July 16th 07, 05:53 AM posted to rec.aviation.piloting
RomeoMike
external usenet poster
 
Posts: 136
Default Heart trouble



Mortimer Schnerd, RN wrote:



Thank you. I was beginning to think I'd lost it. Though, as I think about it,
the day is still young....


From past posts, I think I remember that you really are an RN; so you
might be
interested that Coumadin is a crystallized form of warfarin sodium.
Crystallizing
the warfarin (to make Coumadin) is supposed to get rid of some
impurities that have been in some
generic warfarin preparations. But aside from that, they are chemically
the same.
 




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